Grade lineup

  • The Sustained Release Grade has exceptional ability to make protein or peptide complexes in high volumes. Furthermore, since in situ depot formation occurs under an in vivo environment, it is especially suitable for subcutaneous sustained release.
  • The Solubility Enhancement Grade is markedly able to make complexes of poor water-soluble APls in high volumes. In addition, since the dispersed state is maintained even under an in vivo environment, it is notably suitable as a solubilizer that can be administered intravenously.

Sustained Release Grade

In situ depot formation in the subcutis

Solubility Enhancement Grade

Circulation in the body

Grade lineup

Grade Sustained Release Grade Solubility Enhancement Grade
Sonanos™ PG Sonanos™ DS
Main target Sustained release of APIs
after SC administration		 Solubility enhancement of poorly
water-soluble APIs
Expected
functions		 In situ depot sustained release Improvement of solubility
Competitive
features
  • No chemical conjugation necessary
    (vs. PEGylation)
  • Applicable to protein
    (vs. PLGA-MS)
  • Simple formulation process
    (vs. PLGA-MS)
  • Aseptic filtration available
  • Higher solubility enhancement ability
    (vs. polysorbate 80, CyD)
  • Applicable for large molecules
    (vs. CyD)
  • Improved safety
    (vs. existing solubilizers)
Sonanos™ PG Sonanos™ DS
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