Sonanos™ can greatly improve the solubility of poorly water-soluble APIs with low toxicity compared with existing solubilizers. In particular, it can dramatically improve the solubility of medium-sized molecules (natural peptides, non-natural macrocyclic peptides, nature’s macrocycle).

Solubility enhancement of poorly water-soluble peptides

Cyclic peptide solubility was dramatically improved with
2.4% concentration of Sonanos™

Solubility enhancement of poorly water-soluble small molecules

SM solubility was improved with
only 0.1% concentration of Sonanos™

TOP