About physical properties
Q. What is the form of final product?
A. Final product form is white to pale yellow solid.
Q. Do you have any data of storage stability of Sonanos™?
A. Please check the user guides.
Q. Do you have any data of pH stability of Sonanos™ aqueous solution?
A. We recommend the range of pH 5.5-11 condition for Sonanos™ aqueous solution.
Q. Is it possible for Sonanos™ aqueous solution to be sterile-filtered?
A. It can be aseptic filtered. However high concentration Sonanos™ aqueous solution may be difficult to sterilize filtration. Please check the user guides for recommended conditions for formulation process parameter.
Q. What is the gel-forming condition of sustained release grade?
A. Sustained release grade of Sonanos™ get gel-form in certain amount of salt response, not temperature response.
In water, sustained release grade can maintein disperded stable nano particle. Once get inside of body it gets gel-form.
About formulations
Q. How can I dissolve Sonanos™?
A. You can dissolve Sonanos™ in all grade by Just mixing in water.
Q. What is the general protocol for formulation of Sonanos™?
A.Please check the user guides for detailed information. Typical formulation process and recommended conditions are described in the user guides. Or please contact us and we can share the formulation data of proper condition.
Q. What kind of APIs are solubilized by Sonanos™ in particular?
A. Sonanos™ can solubilize variety of APIs, in particular cyclic peptides.
Q. What kind of proteins can be loaded to Sonanos™?
A. Sonanos™ can load various Mw, electric charge of protein. In particular, proteins with strong surface hydrophobisity are loaded higher. Please check the user guides.
Q. Can I load nucleic acid to Sonanos™?
A. We expect that nucleic acid itself is not easy to be loaded because of the high hydrophilisity.
Q. Is there any buffer which may affect the function of Sonanos™?
A. Depend on concentration, salt may affect the function of Sonanos™. Please contact us if you plan to use salt for your study.
Others
Q. Do you have any safety data of Sonanos™?
We have some non-GLP safety data. Please contact us.
Q. Is Sonanos™ derived from any animal or cell culture derived products?
A. Sonanos™ is not derived from any animal or cell culture derived products.
Q. Can you provide GMP grade of Sonanos™?
A. We are preparing production of sample equivalent to GMP.
Q. Can I get more detail information about Sonanos™ function?
A. We will present or share you some detail information individually. Please contact us.
Q. Do I need to sign any contract to evaluate Sonanos™?
A. We can provide samples under MTA during feasibility study.