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Brand concept
Versatile Facilitation
Expand the potential of DDS formulation.
Fully realizing your potential is a universal goal. To this end, the principle of Versatile Facilitation guides Sonanos™, Asahi Kasei’s Hyaluronic acid nanogel. Sonanos™ is an excipient that provides a variety of functions (Versatility) to better enable the formulation (Facilitation) of specifically targeted DDS. In short, it is a Multifunctional DDS Facilitator.
Structure
- Sonanos™ is composed of Cholesterol-Modified Hyaluronic Acid(CHHA). In water, the cholesterol portions self-associate due to hydrophobic interaction, forming nanometer-scale hydrogels.
- Sonanos™ can load APIs such as proteins, peptides, and small molecules. Multiple grades are available.
Function
Benefits to customers (pharmaceutical companies)
Multifunctional
Tunable solubility enhancement and sustained release profiles through grade selection.
API versatility
Capable of loading a wide range of small molecules, peptides and proteins with various molecular attributes.
Convenience
Formulation can be done simply and easily just by adding Sonanos™.
Safety
Sonanos™ is derived from naturally occuring substances that have high biocompatibility.
Benefits to end-users (patients)
Reduced patient
burden
Fewer injections are needed, reducing the burden on patients.
Reduced side effects
Sonanos™ is made of materials with low toxicity, which reduces concerns about side effects derived from excipients.
Improvement in
anticipated effects
Solving formulation issues, such as poor water solubility, can increase expectations for the anticipated effects of new pharmaceuticals development.
Improvement in
quality of life
Reducing the burden, anxiety and side effects on patients, and raising expectations for the development of new pharmaceuticals, will contribute to the overall improvement of patients’ quality of life.