|
Trehalose is a non-reducing di-saccharide, used for pharmaceutical products as a compactible sugar-type filler and as a taste masking agent, and is marketed worldwide by Asahi Kasei for these applications.
| Chemical structure |
 |
General properties
| Melting point |
97°C |
| Heat of fusion |
57.8KJ/mol |
| Sweetness |
45% that of sucrose |
| Hygroscopicity |
None at less than 90% RH |
| Digestive |
4 kcal/g |
| Solubility |
68.9g (anhydride) / 100g water (at 20°C) |
| Solution stability |
Excellent against pH, heat, amino acids |
| Grade |
P |
G |
| Form |
Powder |
Crystalline granule |
| Application |
Solid dosage |
Liquid dosage |
Note: All values are presented only for the purpose of basic reference and not as specifications.
Features and functions
| •Low reactivity |
•Non-hygroscopicity |
•Heat and pH stability |
| •Stability with basic drug |
•High compactibility |
•Taste and odor-masking effect |
| Aminophylline storage test |
 |
| Hardness vs. disintegration time of plain tablets |
 |
Package
Trehalose P: Polyethylene bag in carboard box
Trehalose G: Polyethylene bag in kraft paper bag
20kg net weight
Further technical data and information are available in the member's site.
Become a member now to access the site. |
|