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CEOLUSTMUF , CEOLUSTMKG , CEOLUSTMPH , CEOLUSTMRC

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>>CEOLUS UF

>>CEOLUS KG

>>CEOLUS PH >>CEOLUS RC

 

With their extraordinary compactibility, CEOLUSTM UF and KG facilitate formulation design and tableting efficiency – particularly for high-dose, small-tablet, and low-compactibility drug implementations.
They are the product of advanced materials and process technology based on decades of leadership in MCC, and complement the standard CEOLUSTM PH and colloidal CEOLUSTM RC series which are widely recognized and trusted for superior function, performance, and quality.

Relationship between compactibility and flowability of placebo tablets

compactibility vs flowability

 

 

UF-711 (x 200)

CeolusTMUF is an MCC powder with unrivalled combination of compactibility and flowability.  Porous, multi-rodform rounded particles.  Facilitates high-dose formulation, low-compactibility drug tableting, reduced tablet size, and enhanced tableting efficiency.

USP / NF
Microcrystalline Cellulose
Ph.Eur.
Microcrystalline Cellulose
JP
Microcrystalline Cellulose

Typical properties

Grade Av. particle size
(μm)
Bulk density
(g/cm3)
Loss on drying
(%)
Repose angle
(degrees)
Package
Type* Net weight (kg)
UF-711 50 0.22 2.0-6.0 42 A 15

*A: Polyethylene bag in kraft paper bag
Note: All values are presented only for the purpose of basic reference and not as specifications.

Features and key applications

In the CEOLUSTM UF series, the particles are porous, rounded composites of multiple micro-rods.  The result is an unparalleled combination of compressibility and flowability.  This enables, in particular:
  1. Reduced tablet size for high-dose formulations and low-compactibility drugs, and freedom from tablet capping.
  2. Heightened efficiency in direct-compression tableting with gravity feeder.

 

 

CEOLUS KG

CeolusTMKG is a maximum-compactibility MCC powder.  Rodform particles.  Facilitates high-dose formulation, low-compactibility drug tableting, and reduced tablet size.

Left hand photo: KG-802, right hand photo: KG-1000 (x 150)

USP / NF
Microcrystalline Cellulose
Ph.Eur.
Microcrystalline Cellulose
JP
Microcrystalline Cellulose

Typical properties

Grade Av. particle size
(μm)
Bulk density
(g/cm3)
Loss on drying
(%)
Repose angle
(degrees)
Package
Type* Net weight (kg)
KG-802 50 0.21 2.0-6.0 49 A 15
KG-1000 50 0.12 2.0-6.0 57 A 10

*A: Polyethylene bag in kraft paper bag
Note: All values are presented only for the purpose of basic reference and not as specifications.

Features and key applications

The unparalleled compactibility of CEOLUSTM KG originates in its distinctive rodform particles.  This compactibility enables, in particular:

  1. Reduced MCC addition and tablet size.
  2. Reduced compression force and superior tableting of pressure-sensitive enzymes, antibiotics, and film-coated granules.

 

Compactibility of placebo tablets


Tri-functional composite profile

 

 

 

CEOLUS PH

The CEOLUSTM PH series of standard MCC powder grades provides excellent, well-proven quality and performance in broad range of pharmaceutical applications.

Left hand photo: PH-101, right hand photo: PH-102 (x 150)

USP / NF
Microcrystalline Cellulose
Ph.Eur.
Microcrystalline Cellulose
JP
Microcrystalline Cellulose

Typical properties

Grade Av. particle size
(μm)
Bulk density
(g/cm3)
Loss on drying
(%)
Repose angle
(degrees)
Package
Type* Net weight (kg)
PH-101 50 0.29 2.0-6.0 45 A 20
PH-102 90 0.30 2.0-6.0 42 A 20
PH-200 180 0.36 2.0-6.0 35 A 20
PH-301 50 0.41 2.0-6.0 41 A 25
PH-302 90 0.43 2.0-6.0 38 A 25
PH-F20JP 20 0.23 7.0 60 B 20

*A: Polyethylene bag in kraft paper bag B: Polyethylene bag in carboard box
Note: All values are presented only for the purpose of basic reference and not as specifications.

 

 


CEOLUS RC

CeolusTMRC is a Colloidal grade for suspension stabilization and granulation enhancement, composed of MCC and sodium carboxymethylcellulose.

PH101¡RC-A591NF

USP / NF
Microcrystalline Cellulose and
Sodium Carboxymethylcellulose
JPE
Microcrystalline Cellulose and
Sodium Carboxymethylcellulose

Typical properties

Grade Assay
for MCC (%)
Assay
for CMC-Na (%)
Vlscosity
(mPa-S)
Package
Type* Net weight (kg)
RC-A591NF 80 8.30-13.70 39-91 A 25

*A: Polyethylene bag in kraft paper bag
Note: All values are presented only for the purpose of basic reference and not as specifications.

Features and functions

Colloidal CEOLUSTM for suspension stabilization and granulation enhancement, composed of MCC and sodium carboxymethylcellulose.

  1. Suspension stabilizer:  Stabilizes syrup and dry-syrup suspensions.
  2. Granulation aid:  Improves dry-syrup and other granulation.

 


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